Description

4-Benzyl-Piperazine-1-Carbonylchloride is a versatile and reactive chemical building block, specifically an acid chloride derivative of a substituted piperazine. This compound is critically important for its role as a key intermediate in the synthesis of more complex molecules, enabling the formation of amide and peptide bonds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides.
• Peptide Mimetics & Linker Chemistry: Facilitates the creation of peptide-like structures and serves as a linker in bioconjugation and prodrug development.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Ligand & Catalyst Preparation: Useful for synthesizing specialized ligands for metal complexes and catalysts.
• Material Science Applications: Potential use in creating functionalized polymers and advanced materials.

Basic Information

Product Name	4-Benzyl-Piperazine-1-Carbonylchloride
CAS No.	63763-66-6
Molecular Formula	C12H15ClN2O
Molecular Weight	238.71 g/mol
Synonyms	1-Benzylpiperazine-4-carbonyl chloride; 4-Benzylpiperazine-1-carbonyl chloride; 1-Benzyl-4-piperazinecarbonyl chloride; 1-(Phenylmethyl)piperazine-4-carboxylic acid chloride; 4-Benzylpiperazine-1-carboxylic acid chloride; 1-Benzylpiperazine-4-carboxylic acid chloride; N-Benzylpiperazine-4-carbonyl chloride; Piperazine-1-carbonylchloride, 4-benzyl-
EINECS	Contact for details

Quality Control

Our 4-Benzyl-Piperazine-1-Carbonylchloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Comprehensive analytical testing is performed, and a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.