Description

2-(Phenylthio)-5α-Cholestan-3-One is a high-purity, synthetic steroidal ketone derivative featuring a phenylthio substituent. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical for the synthesis of complex steroid-based molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal drugs and bioactive compounds.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and chemical transformations.
• Chemical Synthesis: Serves as a precursor for creating modified steroid analogs with potential hormonal, anti-inflammatory, or other pharmacological activities.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for steroid analysis.

Basic Information

Product Name	2-(Phenylthio)-5α-Cholestan-3-One
CAS No.	63608-48-0
Molecular Formula	C₃₃H₅₀OS
Molecular Weight	498.82 g/mol
Synonyms	5α-Cholestan-3-one, 2-(phenylthio)-; 2-(Phenylthio)cholestan-3-one; 2-Phenylthio-5α-cholestan-3-one; 2-(Phenylmercapto)-5α-cholestan-3-one; NSC 338018; 63608-48-0
EINECS	Contact for details

Quality Control

Our 2-(Phenylthio)-5α-Cholestan-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.