Description

Terazosin is a selective α-1 adrenergic receptor antagonist belonging to the quinazoline class of compounds. This active pharmaceutical ingredient (API) is critical for the formulation of antihypertensive and benign prostatic hyperplasia (BPH) medications, offering significant therapeutic value. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in cardiovascular and urological drug development.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of hypertension (high blood pressure).
• Urological Therapeutics: Key component in medications designed to alleviate symptoms of benign prostatic hyperplasia (BPH), such as difficulty in urination.
• Research & Development: Serves as a reference standard and building block in pharmacological studies targeting α-adrenergic pathways.
• Generic Drug Manufacturing: Essential for the production of cost-effective generic versions of branded terazosin medications.
• Formulation Development: Used in the development of various drug delivery systems, including tablets and capsules.
• Clinical Trial Material: Supplied as a high-purity compound for use in pre-clinical and clinical research studies.

Basic Information

Product Name	Terazosin
CAS No.	63590-64-7
Molecular Formula	C19H25N5O4
Molecular Weight	387.44 g/mol
Synonyms	Terazosin Hydrochloride (common salt form); Terazosin HCl; Terazosin Monohydrochloride; Terazosin HCl Dihydrate; Hytrin (brand name); Heitrin; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine; 2-[4-(Tetrahydrofuran-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
EINECS	Contact for details

Quality Control

Our Terazosin is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for identity, assay, purity, and specified impurities. We adhere to cGMP principles where applicable to ensure supply reliability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.