Description

7α,12α-Bis(Acetyloxy)-3α-Hydroxy-5β-Pregnan-20-One is a high-purity, synthetic steroid derivative used as a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its specific stereochemistry and functional groups, which make it a versatile building block for synthesizing more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies and enzyme interaction research.
• Hormone Analog Development: Serves as a precursor in the research and development of novel corticosteroid or other hormonal analogs with targeted therapeutic effects.
• Process Chemistry: Employed in process development and scale-up activities for the production of specialty steroids under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional laboratories for synthetic organic chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Product Name	7α,12α-Bis(Acetyloxy)-3α-Hydroxy-5β-Pregnan-20-One
CAS No.	63533-74-4
Molecular Formula	C₂₅H₃₈O₆
Molecular Weight	434.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-pregnan-20-one 7,12-diacetate; 5β-Pregnan-20-one, 3α,7α,12α-trihydroxy-, 7,12-diacetate; 3α-Hydroxy-7α,12α-bis(acetyloxy)-5β-pregnan-20-one; 7α,12α-Diacetoxy-3α-hydroxy-5β-pregnan-20-one; Pregnan-20-one derivative; Steroid intermediate 63533-74-4
EINECS	Contact for details

Quality Control

Every batch of 7α,12α-Bis(Acetyloxy)-3α-Hydroxy-5β-Pregnan-20-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.