Description

2-Thiophenecarbonyl Chloride,Tetrahydro- is a versatile and highly reactive acyl chloride derivative of tetrahydrothiophene. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the tetrahydrothiophene carbonyl moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the tetrahydrothiophene ring contributes to biological activity.
• Polymer & Material Science: Acts as a monomer or modifying agent for creating specialty polymers with unique electronic or mechanical properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Fundamental building block in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	2-Thiophenecarbonyl Chloride,Tetrahydro-
CAS No.	63521-95-9
Molecular Formula	C5H7ClOS
Molecular Weight	150.62 g/mol
Synonyms	Tetrahydro-2-thiophenecarbonyl chloride; Tetrahydrothiophene-2-carbonyl chloride; 2-Thiophenecarboxylic acid, tetrahydro-, chloride; 2-(Chlorocarbonyl)tetrahydrothiophene; Tetrahydrothiophene-2-carboxylic acid chloride; 2-Carboxy-tetrahydrothiophene chloride; Tetrahydro-2-thienoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonyl Chloride,Tetrahydro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We adhere to cGMP principles where applicable, and our quality assurance includes comprehensive analytical testing. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.