Description

4-Chloro-3-Methylbutanoyl Chloride is a versatile and reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 4-chloro-3-methylbutanoyl moiety, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers and resins with tailored properties.
• Peptide & Protein Research: Employed as an acylating agent in peptide coupling reactions and for modifying biomolecules.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and high-performance pigments.
• Liquid Crystal & OLED Materials: Used in the production of precursors for electronic display and lighting materials.
• Cross-coupling Reactions: Serves as an electrophile in palladium-catalyzed and other metal-mediated coupling reactions.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating novel chemical entities in R&D laboratories.

Basic Information

Product Name	4-Chloro-3-Methylbutanoyl Chloride
CAS No.	63480-13-7
Molecular Formula	C5H8Cl2O
Molecular Weight	155.02 g/mol
Synonyms	4-Chloro-3-methylbutyryl chloride; 3-Methyl-4-chlorobutanoyl chloride; 4-Chloro-3-methylbutanoic acid chloride; Butanoyl chloride, 4-chloro-3-methyl-; 4-Chloro-3-methylbutyroyl chloride; 4-Chloro-β-methylbutyryl chloride; β-Methyl-γ-chlorobutyryl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methylbutanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay (HPLC/GC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC/HPLC)	≤ 2.0% (total)
Density (at 20°C)	~1.18 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.