Description

N(Delta)-(Phosphonoacetyl)-L-Ornithine is a specialized biochemical compound featuring a phosphonoacetyl group linked to the δ-amino group of L-ornithine. This molecule is of significant interest in biochemical research and pharmaceutical development due to its structural similarity to reaction intermediates in key metabolic pathways. It serves as a critical building block and research tool for scientists in life sciences. Its primary utility is found in advanced research applications, particularly in enzymology and medicinal chemistry.

Application

• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, particularly for enzymes involved in amino acid metabolism and polyamine biosynthesis.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor or a pharmacophore model in the development of novel therapeutic agents targeting specific enzymes.
• Enzyme Mechanism Studies: Employed to investigate the catalytic mechanisms of acetyltransferases and other enzymes that interact with ornithine derivatives.
• Metabolic Pathway Analysis: A tool for probing and modulating metabolic pathways such as the urea cycle and arginine biosynthesis in experimental models.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to design and optimize new compounds with potential biological activity.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in biochemistry and molecular biology.

Basic Information

Product Name	N(Delta)-(Phosphonoacetyl)-L-Ornithine
CAS No.	63446-55-9
Molecular Formula	C7H15N2O6P
Molecular Weight	254.18 g/mol
Synonyms	δ-N-(Phosphonoacetyl)-L-ornithine; (S)-2,5-Diamino-5-oxopentylphosphonoacetic acid; L-Ornithine, N5-(phosphonoacetyl)-; Phosphonoacetylornithine; PALO (common abbreviation); N5-Phosphonoacetyl-L-ornithine; NSC 163501; Ornithine derivative, phosphonoacetyl-
EINECS	Contact for details

Quality Control

Our N(Delta)-(Phosphonoacetyl)-L-Ornithine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.