Description

Purin-6-Yl 1-Thio-β-Glucopyranosiduronic Acid is a specialized thioglycoside derivative of a purine base and glucuronic acid, serving as a critical biochemical intermediate. This compound is valued for its role in studying metabolic pathways, particularly those involving nucleoside analogs and glucuronidation processes. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology, antiviral therapies, and enzymology.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly for glucuronosyltransferases and other metabolic enzymes.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis of novel nucleoside-based drug candidates for antiviral and anticancer applications.
• Metabolite Analysis: Employed in analytical laboratories as a standard for the identification and quantification of related metabolites in biological samples via HPLC or LC-MS.
• Enzyme Inhibition Studies: Investigated for its potential to modulate enzyme activity in targeted therapeutic pathways.
• Academic Research: Utilized in universities and research institutes for fundamental studies in glycoscience, medicinal chemistry, and purine metabolism.

Basic Information

Product Name	Purin-6-Yl 1-Thio-β-Glucopyranosiduronic Acid
CAS No.	63425-02-5
Molecular Formula	C11H12N4O7S
Molecular Weight	344.30 g/mol
Synonyms	6-Mercaptopurine 1-thio-β-D-glucuronide; 6-Thiopurine-1-thio-β-D-glucopyranosiduronic acid; 6-MP-1-thio-β-D-glucuronide; 1-Thio-β-D-glucopyranosiduronic acid, purin-6-yl; 6-Thiopurine β-D-glucuronoside; Thioguanine glucuronide analog; NSC 401005; β-1-Thioglucuronide of 6-mercaptopurine
EINECS	Contact for details

Quality Control

Our Purin-6-Yl 1-Thio-β-Glucopyranosiduronic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.