Description

(3B,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid is a key bile acid derivative, also known as hyodeoxycholic acid, with significant importance in pharmaceutical research and development. This compound serves as a critical intermediate and reference standard in the synthesis of therapeutic agents and the study of metabolic pathways. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-purity biochemical building blocks.

Application

• Pharmaceutical Intermediate: A crucial starting material or intermediate in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.
• Biochemical Research: Employed in metabolic pathway studies, particularly research related to cholesterol metabolism, bile acid synthesis, and liver function.
• Active Pharmaceutical Ingredient (API) Development: Investigated for use in the development of APIs for hepatoprotective and choleretic drugs.
• Cell Culture & Diagnostics: Utilized in specialized cell culture media and as a component in diagnostic assay development.

Basic Information

Product Name	(3B,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid
CAS No.	63324-20-9
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	Hyodeoxycholic Acid; 3α,6α-Dihydroxy-5β-cholan-24-oic Acid; HDCA; 3α,6α-Dihydroxy-5β-cholanic Acid; (3α,5β,6α)-3,6-Dihydroxycholan-24-oic Acid; Hyodesoxycholic Acid; α-Hyodeoxycholic Acid; NSC 107428
EINECS	Contact for details

Quality Control

Our (3B,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.