Description

3,6,7,12-Tetrahydroxycholanoic Acid is a polyhydroxylated bile acid derivative, a key intermediate in the synthesis of complex steroidal compounds. Its unique hydroxylation pattern makes it a valuable scaffold for pharmaceutical research and development, particularly in the study of metabolic pathways and receptor interactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel therapeutic agents or diagnostic tools.

Application

• Pharmaceutical Intermediate: Critical starting material or building block for the synthesis of novel steroidal drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in metabolic studies, enzyme inhibition assays, and bile acid pathway research.
• Fine Chemical Synthesis: Serves as a chiral template for the production of complex, high-value specialty chemicals.
• Academic & R&D Laboratories: Employed in universities and research institutions for investigating liver function, cholesterol metabolism, and digestive processes.
• Diagnostic Reagent Development: Potential use in formulating calibrants or components for diagnostic kits targeting liver and metabolic disorders.

Basic Information

Product Name	3,6,7,12-Tetrahydroxycholanoic Acid
CAS No.	63266-88-6
Molecular Formula	C₂₄H₄₀O₆
Molecular Weight	424.57 g/mol
Synonyms	3α,6α,7α,12α-Tetrahydroxy-5β-cholan-24-oic Acid; Tetrahydroxycholanoic Acid; 3,6,7,12-Tetrahydroxy-5β-cholan-24-oic Acid; 5β-Cholan-24-oic acid-3α,6α,7α,12α-tetrol; Cholanoic acid, 3,6,7,12-tetrahydroxy-; 3,6,7,12-Tetrahydroxycholanic Acid
EINECS	Contact for details

Quality Control

Our 3,6,7,12-Tetrahydroxycholanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.