Description

2-(4-Morpholino)Ethyl Isothiocyanate is a versatile organic building block featuring both a reactive isothiocyanate group and a morpholine moiety. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents, including kinase inhibitors and other small-molecule drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiourea derivatives it can form.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation, labeling proteins, or creating activity-based probes due to the electrophilic isothiocyanate group.
• Material Science Research: Employed in the synthesis of functional polymers or ligands for metal-organic frameworks (MOFs) and catalysts.
• Academic & Contract Research: Essential reagent for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	2-(4-Morpholino)Ethyl Isothiocyanate
CAS No.	63224-35-1
Molecular Formula	C7H12N2OS
Molecular Weight	172.25 g/mol
Synonyms	2-Morpholinoethyl isothiocyanate; 4-(2-Isothiocyanatoethyl)morpholine; N-(2-Isothiocyanatoethyl)morpholine; 2-(Morpholin-4-yl)ethyl isothiocyanate; Morpholine, 4-(2-isothiocyanatoethyl)-; 4-(2-Isothiocyanatoethyl)-morpholine; 2-(4-Morpholinyl)ethyl isothiocyanate; N-Morpholinoethyl isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Morpholino)Ethyl Isothiocyanate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including HPLC, NMR, and FTIR analysis, to verify identity and purity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.