Description

Terazosin Hydrochloride is a selective α-1 adrenergic receptor antagonist of the quinazoline class. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of effective and reliable therapeutic agents. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of medications targeting hypertension and benign prostatic hyperplasia (BPH).

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of finished dosage forms for the treatment of hypertension.
• Urological Medications: Essential component in drugs prescribed for the management of benign prostatic hyperplasia (BPH) symptoms.
• Generic Drug Production: Sourcing for the formulation of bioequivalent generic versions of branded α-blocker medications.
• Clinical Research: Utilization in preclinical and clinical studies for investigating cardiovascular and urological pharmacotherapies.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in laboratories.
• Drug Development: Used in R&D for developing new combination therapies or novel drug delivery systems for α-1 blockade.

Basic Information

Product Name	Terazosin Hydrochloride
CAS No.	63074-08-8
Molecular Formula	C19H28ClN5O4
Molecular Weight	425.91 g/mol
Synonyms	Terazosin HCl; Terazosin Monohydrochloride; Terazosin Hydrochloride Anhydrous; Terazosin Hydrochloride Dihydrate; (±)-Terazosin Hydrochloride; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine Monohydrochloride; Hytrin (brand name); Heitrin
EINECS	Contact for details

Quality Control

Our Terazosin Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including identification, assay, impurity profiling, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing compliance with in-house specifications. We support compliance with ICH guidelines and relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.