Description

5-Isoxazoleacetylchloride,3-Methyl-(9Ci) is a specialized heterocyclic acid chloride building block used in advanced organic synthesis. This compound is valued for its high reactivity, enabling the efficient introduction of the 3-methylisoxazole-5-acetyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging the isoxazole ring's bioactivity.
• Chemical Research: Serves as a versatile reagent in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical spaces.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group facilitates coupling reactions to create isoxazole-containing peptide analogs or for bioconjugation applications.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands with unique electronic or coordination properties.

Basic Information

Product Name	5-Isoxazoleacetylchloride,3-Methyl-(9Ci)
CAS No.	62759-29-9
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	3-Methyl-5-isoxazoleacetyl chloride; (3-Methyl-1,2-oxazol-5-yl)acetyl chloride; 3-Methylisoxazole-5-acetyl chloride; 5-Acetyl-3-methylisoxazole chloride; 2-(3-Methylisoxazol-5-yl)acetyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Isoxazoleacetylchloride,3-Methyl-(9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.