Description

1H-Benzimidazole,2-Isothiocyanato-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive isothiocyanate group fused to the benzimidazole scaffold, enabling its use as a key precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactive benzimidazole core.
• Chemical Biology Probe Synthesis: The reactive isothiocyanate group allows for selective conjugation with biomolecules (e.g., proteins, peptides) to create probes for studying biological processes.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with tailored properties.
• Ligand Synthesis for Catalysis: Utilized to prepare novel nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	1H-Benzimidazole,2-Isothiocyanato-(9Ci)
CAS No.	62530-06-7
Molecular Formula	C8H5N3S
Molecular Weight	175.21 g/mol
Synonyms	2-Isothiocyanato-1H-benzimidazole; 1H-Benzimidazole-2-isothiocyanate; 2-Isothiocyanatobenzimidazole; Benzimidazole-2-isothiocyanate; 2-Isothiocyanato-benzimidazole; NSC 163063; AI3-52066
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole,2-Isothiocyanato-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.