Description

1H-Imidazole-2-Carbonyl Chloride, 1-Propyl- (9Ci) is a specialized heterocyclic building block featuring a reactive carbonyl chloride group on the imidazole core. This compound is critical for the synthesis of complex molecules, enabling the introduction of the 1-propylimidazole moiety into target structures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates. Its precise reactivity profile makes it an essential reagent for medicinal chemistry and custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that incorporate heterocyclic structures for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific electronic or binding properties.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring this specific reactive handle.
• Bioconjugation Chemistry: Potential use in modifying biomolecules, where the acyl chloride group can react with amines to form stable amide bonds.

Basic Information

Item	Detail
Product Name	1H-Imidazole-2-Carbonyl Chloride, 1-Propyl- (9Ci)
CAS No.	62366-46-5
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	1-Propyl-1H-imidazole-2-carbonyl chloride; 1-Propylimidazole-2-carbonyl chloride; 2-Carbonyl chloride-1-propylimidazole; 1-Propyl-1H-imidazole-2-carboxylic acid chloride; 1-n-Propylimidazole-2-carbonyl chloride; 62366-46-5; 1-Propylimidazole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Imidazole-2-Carbonyl Chloride, 1-Propyl- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.