Description

1-Methyl-1H-Imidazole-2-Carbonyl Chloride, 97% is a high-purity, reactive chemical intermediate essential for constructing complex heterocyclic frameworks. Its primary value lies in its role as a versatile acylating agent, enabling the efficient synthesis of amides and esters under mild conditions. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the production of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing imidazole-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides that require specific imidazole motifs for activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized N-heterocyclic carbene (NHC) ligands and organocatalysts.
• Polymer Chemistry: Employed in the modification of polymers to introduce imidazole functionalities, altering material properties.
• Peptide Mimetics: Facilitates the incorporation of imidazole units into peptide chains to mimic natural structures for biochemical research.
• Custom Chemical Synthesis: A crucial reagent for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	1-Methyl-1H-Imidazole-2-Carbonyl Chloride, 97%
CAS No.	62366-45-4
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	1-Methyl-1H-imidazole-2-carbonyl chloride; 1-Methylimidazole-2-carbonyl chloride; 2-(Chlorocarbonyl)-1-methylimidazole; 1-Methyl-2-imidazolecarbonyl chloride; 1-Methyl-2-carboxyimidazole chloride; N-Methylimidazole-2-carbonyl chloride; 1-Methyl-1H-imidazole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Imidazole-2-Carbonyl Chloride, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the declared specification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.