Description

4-Methyloxazole-5-Carbonyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-methyloxazole-5-carbonyl moiety, a key structural motif in various high-value compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing oxazole heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the oxazole ring contributes to biological activity.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and other functional polymers.
• Peptide Mimetics & Bioconjugation: Acts as an acylating agent for modifying peptides or creating peptide-like structures with enhanced properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for custom chemical synthesis services targeting complex, multi-step organic molecules.

Basic Information

Product Name	4-Methyloxazole-5-Carbonyl Chloride
CAS No.	62348-24-7
Molecular Formula	C5H4ClNO2
Molecular Weight	145.54 g/mol
Synonyms	5-(Chlorocarbonyl)-4-methyloxazole; 4-Methyl-5-oxazolecarbonyl chloride; 4-Methyloxazole-5-carboxylic acid chloride; 5-Oxazolecarbonyl chloride, 4-methyl-; Methyloxazolecarbonyl chloride; Oxazole-5-carbonyl chloride, 4-methyl- derivative
EINECS	Contact for details

Quality Control

Our 4-Methyloxazole-5-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.