Description

4-Oxazolecarbonyl Chloride is a versatile and highly reactive acid chloride derivative of oxazole, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the oxazolecarbonyl moiety, a key structural feature in numerous high-value compounds. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing heterocyclic cores.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that require the oxazole scaffold.
• Peptide Mimetics & Drug Discovery: Employed to create peptide analogs and probe molecules in medicinal chemistry research.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	4-Oxazolecarbonyl Chloride
CAS No.	62348-20-3
Molecular Formula	C4H2ClNO2
Molecular Weight	131.52 g/mol
Synonyms	4-Oxazolecarboxylic Acid Chloride; Oxazole-4-carbonyl Chloride; 4-Carboxyoxazole Chloride; 1,3-Oxazole-4-carbonyl Chloride; 4-Oxazolylcarbonyl Chloride; Isoxazole-4-carbonyl Chloride (common misnomer); 4-Oxazolecarboxylic acid, chloride
EINECS	Contact for details

Quality Control

Our 4-Oxazolecarbonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.