Description

N2,N7-Dimethylguanosine is a chemically modified nucleoside derivative of guanosine, featuring methylation at the N2 and N7 positions of the purine base. This specific modification is of significant interest in biochemical and pharmaceutical research for studying nucleic acid structure, function, and epigenetic regulation. It serves as a critical reference standard and building block for researchers and manufacturers in the fields of nucleoside chemistry, medicinal chemistry, and life science research.

Application

• Biochemical Research: Used as a reference standard and reagent in studies of RNA modification, structure, and function.
• Medicinal Chemistry: Serves as a key intermediate or precursor in the synthesis of novel nucleoside analogs with potential therapeutic applications.
• Pharmaceutical Development: Employed in the research and development of antiviral or anticancer agents targeting nucleic acid metabolism.
• Life Science Tools: Utilized in the production of specialized probes, labeled nucleotides, or other molecular biology reagents.
• Academic Research: Fundamental studies in epigenetics, enzymology, and chemical biology to understand methylation patterns and their biological consequences.

Basic Information

Product Name	N2,N7-Dimethylguanosine
CAS No.	62122-07-0
Molecular Formula	C₁₂H₁₇N₅O₅
Molecular Weight	311.30 g/mol
Synonyms	N²,N⁷-Dimethylguanosine; 2,7-Dimethylguanosine; Guanosine, N2,N7-dimethyl-; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,7-dimethyl-3H-purin-6-one; 2,7-Dimethyl-9-β-D-ribofuranosylguanine; N(2),N(7)-Dimethylguanosine
EINECS	Contact for details

Quality Control

Our N2,N7-Dimethylguanosine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.