Description

1H-Indole-2-Carbonyl Chloride, 5-Methoxy- (9Ci) is a high-value, reactive chemical intermediate belonging to the indole class of heterocyclic compounds. Its core value proposition lies in its role as a versatile acylating agent, enabling the efficient synthesis of complex amides and esters for advanced research and development. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated organic materials. Its specific structure makes it a key building block for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: Acts as a reactive acyl chloride for introducing the 5-methoxyindole-2-carbonyl moiety into more complex molecular architectures in academic and industrial labs.
• Material Science Research: Employed in the creation of specialized organic compounds for advanced materials, such as organic semiconductors or photoresists.
• Bioconjugation Chemistry: Facilitates the labeling or modification of biomolecules (like peptides) for diagnostic or therapeutic applications.

Basic Information

Product Name	1H-Indole-2-Carbonyl Chloride, 5-Methoxy- (9Ci)
CAS No.	62099-65-4
Molecular Formula	C10H8ClNO2
Molecular Weight	209.63 g/mol
Synonyms	5-Methoxy-1H-indole-2-carbonyl chloride; 5-Methoxyindole-2-carbonyl chloride; 2-(Chlorocarbonyl)-5-methoxy-1H-indole; 5-Methoxy-1H-indole-2-carboxylic acid chloride; 5-Methoxyindole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carbonyl Chloride, 5-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.