Description

1-Adamantyloxycarbonyl Fluoride is a specialized fluorinating reagent and a key building block in advanced organic synthesis. Its value lies in the unique reactivity of the adamantyloxycarbonyl (Adoc) protecting group, which offers enhanced stability under acidic conditions compared to traditional carbamates. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules, peptides, and novel materials where selective protection and deprotection strategies are critical.

Application

• Peptide Synthesis: Used as a reagent for introducing the Adoc (1-adamantyloxycarbonyl) protecting group on amino acids, offering superior acid stability during solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a crucial fluorinating and protecting group agent in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides, where its unique properties facilitate the construction of stable, bioactive molecular frameworks.
• Material Science: Acts as a precursor or modifying agent in the creation of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of activity-based probes and labeled compounds for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	1-Adamantyloxycarbonyl Fluoride
CAS No.	62087-82-5
Molecular Formula	C11H15FO2
Molecular Weight	198.23 g/mol
Synonyms	Adoc-F; 1-Adamantyl Chloroformate Fluoride; 1-Adamantyloxycarbonyl Fluoride; 1-Adamantyl Carbonyl Fluoride; 1-Ada-O-COF; Adamant-1-yloxycarbonyl Fluoride; (Adamantan-1-yloxy)carbonyl Fluoride; 1-Adamantanecarboxylic Acid Fluoride, 1-Adamantyl Ester
EINECS	Contact for details

Quality Control

Our 1-Adamantyloxycarbonyl Fluoride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.