Description

(17S,20S)-5α-Pregnane-3β,5,6β,8,12β,14β,17,20-Octol 12-[(E)-3-Phenylpropenoate] is a high-purity, multi-hydroxylated pregnane derivative with a specific cinnamate esterification at the 12-position. This compound matters as a sophisticated chemical intermediate and reference standard, offering a defined stereochemical framework for advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in steroid chemistry, drug discovery, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Reference Standard: High-purity material for analytical method development, validation, and quality control in regulatory submissions.
• Biochemical Research: Probe for studying enzyme interactions, receptor binding, and metabolic pathways related to steroid hormones.
• Process Chemistry: Starting material or advanced intermediate in the development of scalable, GMP-compliant synthetic routes.
• Academic Research: Tool compound for investigating structure-activity relationships (SAR) in medicinal chemistry programs.
• Custom Synthesis: Precursor for the preparation of specialized derivatives, labeled compounds, or conjugates for diagnostic applications.

Basic Information

Item	Detail
Product Name	(17S,20S)-5α-Pregnane-3β,5,6β,8,12β,14β,17,20-Octol 12-[(E)-3-Phenylpropenoate]
CAS No.	62073-77-2
Molecular Formula	C30H40O9
Molecular Weight	544.64 g/mol
Synonyms	12-O-Cinnamoyl-5α-pregnane-3β,5,6β,8,12β,14β,17,20-octol; (17S,20S)-5α-Pregnane-3β,5,6β,8,12β,14β,17,20-octol 12-(E)-cinnamate; 5α-Pregnane-3β,5,6β,8,12β,14β,17,20-octol 12-cinnamate; Pregnane octol cinnamate derivative; Steroid polyol cinnamate ester; CAS 62073-77-2
EINECS	Contact for details

Quality Control

Our (17S,20S)-5α-Pregnane-3β,5,6β,8,12β,14β,17,20-Octol 12-[(E)-3-Phenylpropenoate] is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.