Description

3-Maleimidobenzoic Acid Chloride is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is critical for introducing maleimide functionality into target molecules, enabling stable covalent bonding. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for creating specialized polymers, linkers, and protein conjugates.

Application

• Bioconjugation Reagent: A key building block for synthesizing heterobifunctional crosslinkers used in antibody-drug conjugates (ADCs) and protein labeling.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs that require targeted maleimide coupling.
• Polymer Modification: Functionalizes polymers and hydrogels to introduce reactive sites for further chemical grafting or biomolecule attachment.
• Surface Immobilization: Enables the covalent attachment of biomolecules (e.g., peptides, proteins) to sensor chips, nanoparticles, and diagnostic assay platforms.
• Materials Science Research: Serves as a precursor for creating novel functional materials with tailored thermal or mechanical properties.
• Peptide Synthesis: Used to incorporate maleimide groups into synthetic peptides for site-specific conjugation.

Basic Information

Product Name	3-Maleimidobenzoic Acid Chloride
CAS No.	61960-57-4
Molecular Formula	C11H6ClNO3
Molecular Weight	235.62 g/mol
Synonyms	3-(Maleimidoyl)benzoyl Chloride; 3-Maleimidobenzoyl Chloride; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoyl Chloride; 1-(3-Chlorocarbonylphenyl)pyrrole-2,5-dione; Maleimidobenzoic Acid Chloride; MBAC; 3-Maleimidobenzoic Acid, Acid Chloride
EINECS	Contact for details

Quality Control

Our 3-Maleimidobenzoic Acid Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by multiple analytical techniques, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.