Description

trans-4-Nitrocinnamoyl Chloride is a versatile and reactive organic intermediate belonging to the class of cinnamic acid derivatives. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing the cinnamoyl moiety for potential therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Bioconjugation: Serves as an acylating agent for modifying amino acids, peptides, or other biomolecules to study structure-activity relationships or create targeted probes.
• Liquid Crystal & OLED Material Research: Acts as a building block for synthesizing advanced organic materials with specific electronic or optical properties.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to create specialty polymers with unique characteristics.
• Chemical Biology Probes: Utilized to create labeled compounds for investigating biological pathways and target engagement.

Basic Information

Product Name	trans-4-Nitrocinnamoyl Chloride
CAS No.	61921-33-3
Molecular Formula	C9H6ClNO3
Molecular Weight	211.60 g/mol
Synonyms	(E)-4-Nitrocinnamoyl Chloride; (E)-3-(4-Nitrophenyl)acryloyl Chloride; 4-Nitro-trans-cinnamoyl Chloride; trans-3-(4-Nitrophenyl)-2-propenoyl Chloride; (2E)-3-(4-Nitrophenyl)prop-2-enoyl Chloride; p-Nitrocinnamoyl Chloride; 4-Nitrocinnamic Acid Chloride
EINECS	Contact for details

Quality Control

Our trans-4-Nitrocinnamoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.