Description

5'-Methylthiotubercidin is a chemically modified nucleoside analog with significant biological activity. This compound is valued for its role as a potent and selective inhibitor of specific cellular enzymes, making it a crucial tool in biochemical and pharmacological research. It is primarily utilized by researchers in the fields of oncology, virology, and molecular biology to study cellular signaling pathways and develop novel therapeutic strategies.

Application

• Biochemical Research: Used as a key reagent in enzymatic studies, particularly for investigating methylthioadenosine phosphorylase (MTAP) and related purine salvage pathways.
• Oncology Research: Serves as a research tool to study tumor cell metabolism, apoptosis, and to evaluate potential anti-cancer agents targeting nucleotide metabolism.
• Antiviral Research: Investigated for its potential inhibitory effects on viral replication mechanisms in various virology studies.
• Pharmaceutical Intermediates: Acts as a sophisticated building block or reference standard in the synthesis and development of novel nucleoside-based pharmaceuticals.
• Cell Signaling Studies: Employed to modulate intracellular signaling cascades, helping to elucidate the role of specific adenosine derivatives in cellular function.

Basic Information

Product Name	5'-Methylthiotubercidin
CAS No.	61893-98-9
Molecular Formula	C12H16N6O3S
Molecular Weight	324.36 g/mol
Synonyms	5'-Deoxy-5'-(methylthio)tubercidin; 5'-Methylthio-5'-deoxytubercidin; 7-Deaza-5'-methylthioadenosine; MT-Tubercidin; 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5'-methyl sulfide; 5'-S-Methyl-5'-thiotubercidin
EINECS	Contact for details

Quality Control

Our 5'-Methylthiotubercidin is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.