Description

5-Hydroxyisophthaloyl Dichloride is a high-purity, reactive diacid chloride derivative of isophthalic acid, serving as a critical building block in advanced polymer synthesis. Its value lies in the dual functionality of the acid chloride groups and the phenolic hydroxyl group, enabling the creation of novel polyesters, polyamides, and specialty monomers with tailored properties. This compound is essential for R&D chemists and production engineers in the pharmaceutical intermediates, high-performance polymer, and specialty chemical sectors seeking to develop materials with enhanced thermal stability, mechanical strength, or specific functional groups.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules, particularly those requiring isophthalate-based scaffolds.
• High-Performance Polymer Synthesis: Monomer for producing specialty polyesters, polyamides (aramids), and polycarbonates with superior thermal and mechanical properties for engineering plastics and fibers.
• Liquid Crystal Polymer (LCP) Production: Building block for aromatic monomers used in the manufacture of high-temperature, dimensionally stable LCPs for electronics and precision components.
• Crosslinking Agent: Used to introduce crosslinks into polymer networks, enhancing chemical resistance, hardness, and thermal stability of coatings, adhesives, and composites.
• Dendrimer and Hyperbranched Polymer Synthesis: Serves as a multifunctional core or branching unit in the controlled synthesis of complex, three-dimensional macromolecular architectures.
• Specialty Chemical Intermediate: Intermediate for further derivatization to esters, amides, or other functionalized compounds used in agrochemicals, dyes, and photoinitiators.

Basic Information

Product Name	5-Hydroxyisophthaloyl Dichloride
CAS No.	61842-44-2
Molecular Formula	C8H4Cl2O3
Molecular Weight	219.02 g/mol
Synonyms	5-Hydroxyisophthalic Acid Dichloride; Isophthaloyl Chloride, 5-Hydroxy-; 1,3-Benzenedicarbonyl Chloride, 5-Hydroxy-; 5-Hydroxybenzene-1,3-dicarbonyl Dichloride; 5-Hydroxy-1,3-benzenedicarboxylic Acid Dichloride; 5-Hydroxylsophthalic Dichloride; 5-Hydroxyisophthalic Dichloride
EINECS	Contact for details

Quality Control

Our 5-Hydroxyisophthaloyl Dichloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by titration, identification by FT-IR, and impurity profiling by HPLC/GC. We provide full traceability and Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as water, alcohols, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.