Description

Estra-1,3,5(10),7-Tetraene-3,17Alpha-Diol Diacetate is a high-purity steroid derivative, specifically a diacetate ester of a tetraene estradiol analog. This compound is a critical advanced pharmaceutical intermediate used in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of specialized steroid hormones and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) research, and the development of new drug candidates targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using techniques like HPLC and LC-MS.
• Biochemical Research: Employed in studies investigating estrogen receptor binding, metabolism, and the biochemical pathways of steroid hormones.

Basic Information

Item	Detail
Product Name	Estra-1,3,5(10),7-Tetraene-3,17Alpha-Diol Diacetate
CAS No.	61786-04-7
Molecular Formula	C22H26O4
Molecular Weight	354.44 g/mol
Synonyms	3,17α-Dihydroxyestra-1,3,5(10),7-tetraene 3,17-diacetate; Estra-1,3,5(10),7-tetraene-3,17α-diol diacetate; 3,17α-Diacetoxyestra-1,3,5(10),7-tetraene; δ1,3,5(10),7-Estratetraene-3,17α-diol diacetate; 17α-Estradiol-3,17-diacetate (tetraene analog); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10),7-Tetraene-3,17Alpha-Diol Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant analytical methods. Our quality commitment aligns with cGMP principles suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.