Description

Guanosine, Periodate Oxidized,*Borohydride Reduced is a chemically modified nucleoside derivative, specifically a reduced dialdehyde derivative of guanosine. This compound is a critical intermediate and biochemical tool, valued for its reactive aldehyde groups that have been stabilized by reduction. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced nucleic acid chemistry, bioconjugation, and the development of novel therapeutic agents and diagnostic probes.

Application

• Bioconjugation Chemistry: Acts as a key linker or spacer for attaching biomolecules (e.g., proteins, peptides, oligonucleotides) to surfaces, particles, or other molecules.
• Nucleic Acid Research: Used in the study of RNA structure, function, and modification, as well as in the synthesis of modified oligonucleotides.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of nucleotide-based prodrugs, antiviral agents, and other bioactive compounds.
• Diagnostic Probe Development: Employed in the creation of labeled probes for assays, imaging, and detection systems due to its modifiable structure.
• Cross-linking Agent: Utilized in materials science and biochemistry to create cross-linked networks or stabilized structures.
• Enzyme Substrate Studies: Applied in research to investigate the activity and mechanism of nucleoside-processing enzymes.

Basic Information

Product Name	Guanosine, Periodate Oxidized,*Borohydride Reduced
CAS No.	61773-91-9
Molecular Formula	C10H15N5O5
Molecular Weight	285.26 g/mol
Synonyms	Periodate-Oxidized Guanosine, Reduced; 2'-Deoxy-2',3'-didehydro-2',3'-dideoxyguanosine (derivative); Guanosine dialcohol; Reduced Oxidized Guanosine; Guanosine-2',3'-dialdehyde, reduced; 9-[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one (oxidized/reduced form); Nucleoside Modification Intermediate; G-Ox-Red
EINECS	Contact for details

Quality Control

Our Guanosine, Periodate Oxidized,*Borohydride Reduced is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are available upon request to ensure transparency and meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.