Description

Succinyl Cyclic Gmp-Tyrosine Methyl Ester CAS NO 61756-21-6 is a chemically modified nucleotide derivative, specifically a succinylated and methylated analog of cyclic GMP tyrosine. This compound is a critical biochemical tool and a key intermediate in advanced research and development. It is primarily utilized by pharmaceutical researchers, diagnostic developers, and academic institutions working on signal transduction pathways, enzyme assays, and the synthesis of novel probes. The product's defined structure enables precise study and modulation of cyclic nucleotide-dependent processes.

Application

• Biochemical Research: Essential as a substrate, inhibitor, or standard in studies of phosphodiesterases (PDEs), protein kinases, and other cyclic nucleotide-binding proteins.
• Pharmaceutical Development: Serves as a key synthetic intermediate or a pharmacologically active compound in the discovery of drugs targeting cardiovascular, neurological, and inflammatory diseases.
• Diagnostic Assay Development: Used in the formulation of enzyme-linked immunosorbent assays (ELISAs), radioimmunoassays (RIAs), and other kits for detecting cyclic nucleotide levels.
• Cell Signaling Studies: Applied in cellular assays to investigate the role of cGMP and tyrosine phosphorylation in signal transduction cascades.
• Probe Synthesis: Acts as a precursor for the synthesis of fluorescently labeled or biotinylated probes for imaging and detection applications.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes exploring molecular biology, cell biology, and pharmacology.

Basic Information

Product Name	Succinyl Cyclic Gmp-Tyrosine Methyl Ester
CAS No.	61756-21-6
Molecular Formula	C₂₀H₂₄N₇O₁₂P
Molecular Weight	585.42 g/mol
Synonyms	Succinyl cGMP Tyrosine Methyl Ester; 2'-O-Succinylguanosine 3',5'-cyclic monophosphate tyrosine methyl ester; ScGMP-TME; cGMP Tyrosine Methyl Ester Succinate; N²,2'-O-Disuccinylguanosine 3',5'-cyclic monophosphate tyrosine methyl ester; Cyclic GMP Succinyl Tyrosine Methyl Ester; 8-Bromoguanosine 3',5'-cyclic monophosphate tyrosyl methyl ester succinate (common related analog); SCGMP-Tyr-OMe
EINECS	Contact for details

Quality Control

Every batch of Succinyl Cyclic Gmp-Tyrosine Methyl Ester is manufactured and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate and keep under inert atmosphere if possible. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.