Description

5-Fluoro-2'-o-Methyluridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel therapeutic agents, particularly in the field of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based prodrugs and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced antiviral and anticancer nucleoside analogs.
• Antiviral Research: Used in the development of potential therapeutic agents targeting viral polymerases.
• Oncology Research: Investigated as a component in prodrug systems designed for targeted cancer therapy.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and related pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Used in scaling up synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Fluoro-2'-o-Methyluridine
CAS No.	61671-80-5
Molecular Formula	C10H13FN2O6
Molecular Weight	276.22 g/mol
Synonyms	2'-O-Methyl-5-fluorouridine; 5-Fluoro-2'-O-methyluridine; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl)pyrimidine-2,4-dione; 5-F-2'-OMe-Urd; 5-Fluoro-2'-O-methyl-uridine; 2'-O-Methyl-5-fluoro-uridine; 5-Fluorouridine 2'-methyl ether
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2'-o-Methyluridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.