Description

27-Nor-3,7,12-Trihydrocoprostan-24-One is a high-purity steroidal ketone derivative, identified by CAS No. 61628-32-8. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for analytical research and development. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and biotechnology sectors for the synthesis and analysis of complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) in HPLC, GC-MS, and NMR analyses within laboratory settings.
• Biochemical Research: Employed in metabolic pathway studies and as a substrate or inhibitor in enzymatic assays related to steroid metabolism.
• Process Chemistry: Serves as a precursor for scaling up production processes under current Good Manufacturing Practices (cGMP).
• Academic Research: Utilized in universities and research institutes for investigating steroid chemistry, molecular structure, and biological activity.

Basic Information

Product Name	27-Nor-3,7,12-Trihydrocoprostan-24-One
CAS No.	61628-32-8
Molecular Formula	C26H44O2
Molecular Weight	388.63 g/mol
Synonyms	27-Nor-3α,7α,12α-Trihydroxy-5β-cholestan-24-one; 3α,7α,12α-Trihydroxy-27-nor-5β-cholestan-24-one; 27-Norcholestane-24-one derivative; Steroid ketone intermediate; 5β-Cholestane-24-one, 27-nor-3α,7α,12α-trihydroxy-; (24-Oxo-27-norcholestan-3α,7α,12α-triol)
EINECS	Contact for details

Quality Control

Our 27-Nor-3,7,12-Trihydrocoprostan-24-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.