Description

4H-Pyran-3-Carbonyl Chloride, 4-Thioxo- (9Ci) is a specialized heterocyclic building block characterized by its reactive carbonyl chloride and thioxo functional groups. This compound matters as a high-value synthetic intermediate, enabling the efficient construction of complex molecular architectures in advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D laboratories for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing modified pyran or thiopyran scaffolds for therapeutic applications.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its heterocyclic structure to create molecules with specific biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex, high-value specialty chemicals and custom organic compounds.
• Material Science Research: Employed in the development of advanced organic materials, where its functional groups can be used to modify polymer backbones or create novel monomers.
• Academic & Industrial R&D: A valuable reagent for methodological chemistry research, exploring new reactions and synthetic pathways involving sulfur and oxygen heterocycles.

Basic Information

Product Name	4H-Pyran-3-Carbonyl Chloride, 4-Thioxo- (9Ci)
CAS No.	61611-81-2
Molecular Formula	C6H3ClO2S
Molecular Weight	174.60 g/mol
Synonyms	4-Thioxo-4H-pyran-3-carbonyl chloride; 4H-Pyran-3-carbonyl chloride, 4-thioxo-; 4-Oxo-4H-thiopyran-3-carbonyl chloride; 3-Carbonyl chloride-4-thioxo-4H-pyran; 4-Thioxopyran-3-carbonyl chloride; Thiopyran-4-one-3-carbonyl chloride; 61611-81-2
EINECS	Contact for details

Quality Control

Our production of 4H-Pyran-3-Carbonyl Chloride, 4-Thioxo- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and synthesis applications. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.