Description

4,4'-Diisothiocyano-2,2'-Dihydrostilbenedisulfonic Acid is a specialized organic compound belonging to the class of stilbene derivatives, characterized by its reactive isothiocyanate and sulfonic acid functional groups. This compound matters as a versatile bifunctional cross-linking agent and fluorescent probe precursor, enabling critical research and development in advanced material and life sciences. It is primarily needed by manufacturers and research institutions in the pharmaceutical, bioconjugation, and polymer chemistry sectors for developing targeted drug delivery systems, diagnostic assays, and functional polymers.

Application

• Bioconjugation and Protein Labeling: Acts as a key reagent for covalently attaching fluorescent tags, drugs, or other molecules to proteins, antibodies, and peptides via its reactive isothiocyanate groups.
• Fluorescent Probe Synthesis: Serves as a core scaffold for developing sensitive fluorescent probes and sensors used in bioimaging, cellular staining, and diagnostic assays.
• Polymer Cross-Linking: Utilized as a cross-linker in the synthesis of hydrogels, resins, and other polymeric materials to modify their mechanical properties and stability.
• Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents, particularly in creating antibody-drug conjugates (ADCs).
• Material Science Research: Used in surface modification and the creation of functionalized materials with specific optical or chemical properties.
• Diagnostic Kit Manufacturing: Incorporated into the production of ELISA kits and other immunoassay components for disease detection.

Basic Information

Product Name	4,4'-Diisothiocyano-2,2'-Dihydrostilbenedisulfonic Acid
CAS No.	61481-03-6
Molecular Formula	C₁₆H₁₀N₂O₆S₄
Molecular Weight	454.52 g/mol
Synonyms	DIDS; 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic Acid; DIDS Acid; H₂DIDS; 4,4'-DIDS; 4,4'-Diisothiocyanatodihydrostilbene-2,2'-disulfonate; Stilbene Disulfonic Acid DIDS
EINECS	Contact for details

Quality Control

Our 4,4'-Diisothiocyano-2,2'-Dihydrostilbenedisulfonic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.