Description

4-[[(S)-3-Amino-5-(1-Methylguanidino)-1-Oxopentyl]Amino]-1-(4-Amino-2-Oxo-1(2H)-Pyrimidinyl)-1,3,4-Trideoxy-β-D-Ribo-Hexopyranuronic Acid is a sophisticated nucleoside analogue derivative of significant interest in advanced pharmaceutical research and development. This compound's complex structure, featuring a modified ribose sugar and a cytosine base linked to an arginine-like side chain, makes it a critical intermediate for synthesizing novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers working on antiviral drugs, enzyme inhibitors, and targeted molecular probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving reverse transcriptase or other nucleic acid-processing enzymes.
• Proteomics & Molecular Biology: Serves as a specialized component for modifying oligonucleotides or creating affinity labels and probes.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	4-[[(S)-3-Amino-5-(1-Methylguanidino)-1-Oxopentyl]Amino]-1-(4-Amino-2-Oxo-1(2H)-Pyrimidinyl)-1,3,4-Trideoxy-β-D-Ribo-Hexopyranuronic Acid
CAS No.	61461-71-0
Molecular Formula	C₁₇H₂₈N₈O₇
Molecular Weight	456.46 g/mol
Synonyms	NSC 401005; 1-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-[[(2S)-3-amino-5-[(E)-N'-methylcarbamimidamido]-1-oxopentyl]amino]-1,3,4-trideoxy-β-D-ribo-hexopyranuronic acid; 1-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-4-[[(2S)-3-amino-5-[(E)-N'-methylcarbamimidamido]-1-oxopentyl]amino]-1,3,4-trideoxy-β-D-ribo-hexopyranuronic acid; β-D-ribo-Hexopyranuronic acid, 1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-4-[[(2S)-3-amino-5-[(E)-N'-methylcarbamimidamido]-1-oxopentyl]amino]-1,3,4-trideoxy-
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the integrity of this high-value biochemical. Every batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. Our production and control processes are designed to support cGMP compliance for applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.