Description

2,3,3,3-Tetrafluoropropanoyl Bromide is a highly reactive fluorinated acyl bromide building block, essential for introducing the 2,3,3,3-tetrafluoropropanoyl moiety into target molecules. Its primary value lies in enabling the synthesis of advanced fluorinated compounds, which are critical for developing materials with enhanced stability and unique physicochemical properties. This intermediate is particularly vital for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required to modulate biological activity, lipophilicity, and environmental persistence.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated side chains, improving metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymer backbones or side chains, imparting oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex fluorinated organic molecules and exploring new chemical spaces.
• Surfactant & Coating Additives: Used to synthesize fluorinated surfactants and additives for high-performance coatings, films, and surface treatments.

Basic Information

Product Name	2,3,3,3-Tetrafluoropropanoyl Bromide
CAS No.	61444-66-4
Molecular Formula	C3H1BrF4O
Molecular Weight	208.94 g/mol
Synonyms	Perfluoroisopropanoyl Bromide; 2,3,3,3-Tetrafluoro-1-propanoyl Bromide; Tetrafluoropropionyl Bromide; 2,3,3,3-Tetrafluoropropionic Acid Bromide; Bromo(2,3,3,3-tetrafluoropropanoyl); 2,3,3,3-Tetrafluoropropanoyl Bromide; α,α,β,β-Tetrafluoropropionyl Bromide
EINECS	Contact for details

Quality Control

Our 2,3,3,3-Tetrafluoropropanoyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) and at temperatures between 2°C and 8°C for long-term stability. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.