Description

4-Hydroxy-3-Isothiocyanatobutyric Acid Lactone is a specialized heterocyclic compound featuring a reactive isothiocyanate group. This unique structure makes it a valuable intermediate for synthesizing a range of bioactive molecules, including potential pharmaceuticals and agrochemicals. It is primarily sought by research institutions and chemical manufacturers in the life sciences sector for developing novel compounds and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators.
• Bioconjugation Reagent: The reactive isothiocyanate group enables covalent bonding to amines in proteins, peptides, and other biomolecules for labeling and cross-linking applications.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and fine chemicals in organic chemistry.
• Biochemical Probe Development: Utilized in research to create probes for studying enzyme activity, protein function, and cellular processes.

Basic Information

Product Name	4-Hydroxy-3-Isothiocyanatobutyric Acid Lactone
CAS No.	61315-63-7
Molecular Formula	C5H5NO3S
Molecular Weight	159.16 g/mol
Synonyms	3-Isothiocyanato-4-hydroxybutyric acid lactone; 4-Hydroxy-3-isothiocyanatobutyric acid γ-lactone; 3-Isothiocyanato-4-hydroxybutyrolactone; 4-Hydroxy-3-isothiocyanatobutyrolactone; 3-Isothiocyanatodihydro-2(3H)-furanone; 4-Hydroxy-3-isothiocyanato-γ-butyrolactone
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Isothiocyanatobutyric Acid Lactone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, with each shipment. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request and are standard for all research and commercial grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.