Description

2-Thiazolecarbonyl Chloride, 5-Methyl- (9Ci) is a specialized heterocyclic acid chloride derivative that serves as a critical building block in advanced organic synthesis. Its high reactivity makes it an indispensable reagent for introducing the 5-methylthiazole-2-carbonyl moiety into target molecules, enabling the creation of complex chemical architectures. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with thiazole-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiazole ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences industry.
• Academic & Industrial R&D: Fundamental building block for methodological development and exploratory chemistry in heterocyclic compound research.

Basic Information

Product Name	2-Thiazolecarbonyl Chloride, 5-Methyl- (9Ci)
CAS No.	61291-22-3
Molecular Formula	C5H4ClNOS
Molecular Weight	161.61 g/mol
Synonyms	5-Methylthiazole-2-carbonyl chloride; 5-Methyl-2-thiazolecarbonyl chloride; 5-Methyl-1,3-thiazole-2-carbonyl chloride; 2-Carbonyl chloride-5-methylthiazole; 5-Methyl-2-thiophenecarbonyl chloride (common misnomer); 5-Methyl-thiazol-2-carbonyl chloride; 5-Methylthiazol-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Thiazolecarbonyl Chloride, 5-Methyl- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	95.0% - 102.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.