Description

1H-Imidazole-1-Carbonyl Chloride, 2,5-Dihydro-2-Oxo- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce the imidazole carbonyl chloride moiety, facilitating the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredient development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive functional groups.
• Peptide Mimetics & Bioconjugation: Employed to create imidazole-based peptide analogs or for coupling reactions in bioconjugate chemistry.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Chemical Biology Probes: Utilized to synthesize labeled compounds or probes for studying biological pathways and mechanisms.
• Ligand & Catalyst Development: Acts as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	1H-Imidazole-1-Carbonyl Chloride, 2,5-Dihydro-2-Oxo- (9Ci)
CAS No.	61282-43-7
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	2-Oxo-2,5-dihydro-1H-imidazole-1-carbonyl chloride; 1-Imidazolecarbonyl chloride, 2,5-dihydro-2-oxo-; 2,5-Dihydro-2-oxo-1H-imidazole-1-carbonyl chloride; 1H-Imidazole-1-carbonyl chloride, 2,5-dihydro-2-oxo-; Imidazolidine-2-one-1-carbonyl chloride; 1-Carboxyimidazolidin-2-one chloride; Oxoimidazolidinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Carbonyl Chloride, 2,5-Dihydro-2-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.