Description

(3α,5β,7α)-3-[(Ethoxycarbonyl)Oxy]-7-Hydroxycholan-24-Oic Acid Methyl Ester is a high-purity, synthetic bile acid derivative, serving as a critical intermediate in advanced pharmaceutical research and development. Its value lies in its defined stereochemistry and functional groups, which are essential for synthesizing novel therapeutic agents targeting metabolic and liver-related disorders. This compound is primarily needed by pharmaceutical manufacturers and research institutions engaged in the development of steroidal drugs and metabolic pathway modulators.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and therapeutic bile acid analogs.
• Metabolic Research: Used as a reference standard or precursor in studies investigating cholesterol metabolism, bile acid signaling, and liver function.
• Prodrug Development: Serves as a starting material for creating prodrugs with enhanced bioavailability or targeted delivery profiles.
• Chemical Synthesis: Employed in organic synthesis for introducing specific steroidal frameworks with defined hydroxyl and ester functionalities.
• Biochemical Reagent: Utilized in enzymatic studies and as a substrate or inhibitor in assays related to sterol metabolism.

Basic Information

Product Name	(3α,5β,7α)-3-[(Ethoxycarbonyl)Oxy]-7-Hydroxycholan-24-Oic Acid Methyl Ester
CAS No.	61252-49-1
Molecular Formula	C₂₈H₄₆O₇
Molecular Weight	494.67 g/mol
Synonyms	Methyl 3α-(ethoxycarbonyloxy)-7α-hydroxy-5β-cholan-24-oate; 3α-Ethoxycarbonyloxy-7α-hydroxy-5β-cholan-24-oic Acid Methyl Ester; 7α-Hydroxy-3α-[(ethoxycarbonyl)oxy]-5β-cholan-24-oic Acid Methyl Ester; Chenodeoxycholic Acid 3-Ethyl Carbonate Methyl Ester; CDCA 3-Ethyl Carbonate Methyl Ester; (3α,5β,7α)-3-[(Ethoxycarbonyl)oxy]-7-hydroxycholan-24-oic Acid Methyl Ester; 3α-Hydroxy-7α-[(ethoxycarbonyl)oxy]-5β-cholan-24-oic Acid Methyl Ester (isomer)
EINECS	Contact for details

Quality Control

Our (3α,5β,7α)-3-[(Ethoxycarbonyl)Oxy]-7-Hydroxycholan-24-Oic Acid Methyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant GMP guidelines for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.