Description

(R)-Guaifenesin CAS NO 61248-75-7 is the single enantiomer form of the widely used expectorant guaifenesin, offering a high-purity, stereochemically defined active pharmaceutical ingredient (API). This specific chirality is critical for targeted pharmaceutical development and research into stereoselective biological activity. It is essential for manufacturers and research institutions requiring a precise molecular tool for advanced drug formulation, chiral synthesis, and pharmacological studies.

Application

• Pharmaceutical API: Primary use as the active enantiomer in advanced expectorant and mucolytic formulations.
• Chiral Intermediate: Key building block in the asymmetric synthesis of more complex therapeutic molecules.
• Analytical Reference Standard: Used in quality control laboratories for method development and validation of chiral assays.
• Pharmacological Research: Employed in studies to investigate the stereospecific metabolism and receptor binding of guaifenesin.
• High-Purity Chemical Reagent: Serves as a reagent in organic synthesis where the (R)-configuration is required.

Basic Information

Product Name	(R)-Guaifenesin
CAS No.	61248-75-7
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	(R)-(-)-Guaifenesin; (R)-3-(2-Methoxyphenoxy)-1,2-propanediol; (R)-Guaiacol glyceryl ether; (R)-Glyceryl guaiacolate; (R)-Guaiacol glycerol ether; (R)-1,2-Propanediol, 3-(2-methoxyphenoxy)-, (2R)-; (-)-Guaifenesin; (R)-Methoxyphenoxypropanediol
EINECS	Contact for details

Quality Control

Our (R)-Guaifenesin is manufactured under strict quality management systems. It undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to guarantee supply reliability and product consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (R)-enantiomer
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.