Description

Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride is a specialized bicyclic acid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, sterically defined structure is essential for constructing complex molecular architectures with precise stereochemistry. This high-purity intermediate is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and high-value specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its bicyclic framework contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique thermal or mechanical properties.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex, camphor-like odorants and flavor compounds.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and stereoselective transformations.

Basic Information

Product Name	Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl Chloride
CAS No.	61175-88-0
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	2-Exo-Bornane Carbonyl Chloride; 2-Exo-Camphane Carbonyl Chloride; 2-Exo-(1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl)carbonyl Chloride; Exo-2-Camphoroyl Chloride; (1R,2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-carbonyl chloride; Bicyclo[2.2.1]heptane-2-carbonyl chloride, 3,3-dimethyl-, exo-; NSC 334087
EINECS	Contact for details

Quality Control

Our Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by GC or HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and acid chloride nature. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (exo-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.