Description

Papulacandins are a class of natural antifungal lipopeptides, with CAS No. 61036-45-1 representing a key member of this group. These compounds are valued for their potent and specific inhibitory activity against fungal cell wall synthesis, particularly targeting β-(1,3)-glucan synthase. This makes them critical research tools and potential lead compounds in the development of novel antifungal agents for pharmaceutical and agricultural applications. Industries engaged in antifungal discovery, biochemical research, and mycology will find this high-purity reference standard essential for their work.

Application

• Antifungal Research & Development: Serves as a primary reference standard and active pharmaceutical ingredient (API) in the discovery and study of new antifungal drugs.
• Biochemical Mechanism Studies: Used as a specific probe to investigate the function and inhibition of β-(1,3)-glucan synthase in fungal cell wall biosynthesis.
• Agricultural Fungicide Development: Explored as a lead structure for creating novel crop protection agents against pathogenic fungi.
• Microbiology & Mycology: Employed in laboratory studies to understand fungal physiology, resistance mechanisms, and structure-activity relationships (SAR).
• Pharmaceutical Intermediates: Acts as a key intermediate or starting material for the semi-synthesis of more complex antifungal derivatives.
• Quality Control & Standardization: Used as an analytical standard in HPLC, LC-MS, or other methods to ensure the quality and potency of antifungal preparations.

Basic Information

Product Name	Papulacandins
CAS No.	61036-45-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Papulacandin; Papulacandin A; Papulacandin B; Papulacandin complex; L-68778; Antibiotic L 68778; FR 109615; Antifungal lipopeptide papulacandin; β-Glucan synthase inhibitor
EINECS	Contact for details

Quality Control

Our Papulacandins are produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including purity assay and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the results against our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.