Description

5-Thiazolecarbonyl Chloride, 2-Methyl- (9Ci) is a versatile and highly reactive acyl chloride derivative of a substituted thiazole ring. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 2-methylthiazole-5-carbonyl moiety. It is primarily sought after by pharmaceutical and agrochemical research and development teams for the construction of complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole scaffold.
• Material Science Research: Acts as a monomer or coupling agent in the creation of specialized polymers and functional materials.
• Ligand and Catalyst Development: Employed to synthesize novel chelating ligands or organocatalysts for asymmetric synthesis.
• Peptide Mimetics: Useful for incorporating heterocyclic structures into peptide backbones to modify stability and biological properties.
• Chemical Biology Probes: Serves as a reagent for labeling or modifying biomolecules to study biological processes.

Basic Information

Product Name	5-Thiazolecarbonyl Chloride, 2-Methyl- (9Ci)
CAS No.	60971-72-4
Molecular Formula	C5H4ClNOS
Molecular Weight	161.61 g/mol
Synonyms	2-Methylthiazole-5-carbonyl chloride; 2-Methyl-5-thiazolecarbonyl chloride; 2-Methyl-1,3-thiazole-5-carbonyl chloride; 5-Carboxy-2-methylthiazole chloride; 2-Methylthiazol-5-yl carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of our 5-Thiazolecarbonyl Chloride, 2-Methyl- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring consistency and reliability for your critical synthesis workflows. Our products are suitable for use in GMP-oriented development and other regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.