Description

2(3H)-Isoxazolecarbonylchloride,4-Chloro-5-Methyl-3-Oxo-(9Ci) is a specialized heterocyclic building block and acid chloride derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its core value lies in enabling the efficient construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of compounds with potential anti-inflammatory, antimicrobial, or central nervous system activity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the isoxazole moiety imparts specific biological activity.
• Fine Chemical Production: Serves as a versatile precursor for creating complex heterocyclic compounds, dyes, and functional materials in specialty chemical manufacturing.
• Academic & Industrial Research: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry and material science laboratories.
• Peptide Mimetic Synthesis: The acid chloride functionality allows for the introduction of the isoxazole-carbonyl group into molecules, creating peptide backbone mimics or enzyme inhibitors.

Basic Information

Item	Detail
Product Name	2(3H)-Isoxazolecarbonylchloride,4-Chloro-5-Methyl-3-Oxo-(9Ci)
CAS No.	60908-30-7
Molecular Formula	C5H3Cl2NO2
Molecular Weight	179.99 g/mol
Synonyms	4-Chloro-5-methyl-3-oxo-2,3-dihydroisoxazole-2-carbonyl chloride; 4-Chloro-5-methyl-3-oxo-2-isoxazoline-2-carbonyl chloride; 2,3-Dihydro-4-chloro-5-methyl-3-oxoisoxazole-2-carbonyl chloride; 4-Chloro-5-methyl-3-oxo-δ2-isoxazoline-2-carbonyl chloride; 2-Carbonylchloride-4-chloro-5-methyl-3-oxo-2,3-dihydroisoxazole; 4-Chloro-5-methyl-3-oxoisoxazolidine-2-carbonyl chloride; Isoxazole-2-carbonyl chloride, 4-chloro-5-methyl-3-oxo-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 2(3H)-Isoxazolecarbonylchloride,4-Chloro-5-Methyl-3-Oxo-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.