Description

Dimethylaminoacetyl Chloride Hydrochloride is a versatile and reactive chemical intermediate, primarily valued for its role in the synthesis of complex organic molecules. Its importance lies in providing a protected, activated carbonyl moiety for introducing the dimethylaminoacetyl group, a key structural feature in various bioactive compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with cholinergic or neurological activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific amine-functionalized side chains.
• Peptide Mimetics & Modifications: Employed to introduce the dimethylglycine (DMG) moiety or other modified amino acid structures into peptide chains.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexation.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of certain cationic dyes and colorants.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in research institutions and CROs.

Basic Information

Product Name	Dimethylaminoacetyl Chloride Hydrochloride
CAS No.	60853-81-8
Molecular Formula	C4H9Cl2NO
Molecular Weight	158.03 g/mol
Synonyms	2-(Dimethylamino)acetyl Chloride Hydrochloride; N,N-Dimethylglycyl Chloride Hydrochloride; Chloroacetyl Dimethylamine Hydrochloride; DMG-Cl·HCl; Acetyl Chloride, 2-(dimethylamino)-, hydrochloride; (Dimethylamino)acetic Acid Chloride Hydrochloride
EINECS	Contact for details

Quality Control

Our Dimethylaminoacetyl Chloride Hydrochloride is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in polar organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.