Description

Benzoyl Chloride, 5-(Aminocarbonyl)-2-Hydroxy- (9Ci) is a specialized benzoyl chloride derivative that serves as a key multifunctional intermediate in advanced organic synthesis. Its unique structure, featuring both an amide and a phenolic hydroxyl group adjacent to the reactive acid chloride, makes it invaluable for constructing complex molecules with specific functionalization. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to introduce the 2-hydroxy-5-carbamoylbenzoyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a salicylamide-type pharmacophore.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where its bifunctional reactivity is leveraged.
• Dye and Pigment Manufacturing: Serves as a precursor for advanced colorants and optical brighteners due to its ability to form stable amide and ester linkages with chromophores.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal stability or specific binding sites.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.
• Liquid Crystal and OLED Material Production: Used in the synthesis of advanced organic electronic materials that require precise molecular architecture.

Basic Information

Product Name	Benzoyl Chloride, 5-(Aminocarbonyl)-2-Hydroxy- (9Ci)
CAS No.	60795-46-2
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	5-Carbamoyl-2-hydroxybenzoyl chloride; 2-Hydroxy-5-carbamoylbenzoyl chloride; 5-Aminocarbonyl-2-hydroxybenzoyl chloride; 2-Hydroxy-5-aminocarbonylbenzoyl chloride; 5-Carbamoylsalicyloyl chloride; Salicylamide-5-carbonyl chloride; (5-Carbamoyl-2-hydroxyphenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Benzoyl Chloride, 5-(Aminocarbonyl)-2-Hydroxy- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed against comprehensive specifications using validated methods such as HPLC, NMR, and titration. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.