Description

2-Pyridinecarbonyl Chloride, 6-Nitro- (9Ci) is a specialized heterocyclic building block and key reactive intermediate in organic synthesis. Its value lies in the strategic positioning of both a highly reactive acid chloride group and a nitro substituent on the pyridine ring, enabling precise derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating amide-linked pharmacophores and advanced chemical libraries.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its bioisosteric potential.
• Chemical Research & Development: Serves as a versatile precursor for creating complex heterocyclic compounds, metal-organic frameworks (MOFs), and specialized ligands for catalysis.
• Material Science: Employed in the synthesis of functional polymers, dyes, and photoactive materials where the nitro-pyridine moiety imparts specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a 6-nitro-2-pyridinecarbonyl group into target molecules.

Basic Information

Product Name	2-Pyridinecarbonyl Chloride, 6-Nitro- (9Ci)
CAS No.	60780-83-8
Molecular Formula	C6H3ClN2O3
Molecular Weight	186.55 g/mol
Synonyms	6-Nitropicolinoyl Chloride; 6-Nitro-2-pyridinecarbonyl chloride; 6-Nitropyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 6-nitro-; 6-Nitro-2-picolinoyl chloride; 6-Nitropicolinic acid chloride; 6-Nitro-2-pyridylcarbonyl chloride; 6-Nitropicolinoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonyl Chloride, 6-Nitro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.