Description

4-Pyridinecarbonyl Chloride, 2-Nitro- (9Ci) is a versatile and reactive organic intermediate, specifically a functionalized pyridine derivative. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing nitro-substituted pyridine motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pyridine core is essential for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that require specific nitrogen-containing heterocycles.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems due to its reactive acid chloride group.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Pyridinecarbonyl Chloride, 2-Nitro- (9Ci)
CAS No.	60780-81-6
Molecular Formula	C6H3ClN2O3
Molecular Weight	186.55 g/mol
Synonyms	2-Nitroisonicotinoyl chloride; 2-Nitro-4-pyridinecarbonyl chloride; 4-Pyridinecarbonyl chloride, 2-nitro-; Isonicotinoyl chloride, 2-nitro-; 2-Nitroisonicotinic acid chloride; 2-Nitropyridine-4-carbonyl chloride; 4-Carbamoyl-2-nitropyridine hydrochloride (related); 2-Nitro-4-pyridylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarbonyl Chloride, 2-Nitro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for extended storage or after opening. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.