Description

ε-Atp Sodium Salt CAS NO 60777-99-3 is a high-purity biochemical reagent, specifically the sodium salt of adenosine 5'-(γ-thio)triphosphate. This compound is a crucial non-hydrolyzable ATP analog used extensively in enzymatic studies to investigate kinase activity and ATP-dependent processes. It is an essential tool for researchers and manufacturers in the fields of molecular biology, biochemistry, and pharmaceutical development who require reliable, high-quality substrates for their critical assays and production workflows.

Application

• Enzymology Research: As a substrate analog for studying the kinetics and mechanisms of ATP-utilizing enzymes, particularly kinases and ATPases.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) assays to identify and characterize potential kinase inhibitors for drug discovery.
• Biochemical Assay Development: A key component in formulating robust, reproducible assay kits for measuring enzymatic activity in research and diagnostic applications.
• Signal Transduction Studies: Employed to probe phosphorylation events and signaling pathways within cells without being hydrolyzed, allowing for the trapping of reaction intermediates.
• Industrial Enzyme Characterization: Used to test the activity and specificity of enzymes produced for biocatalysis and other industrial bioprocesses.

Basic Information

Product Name	ε-Atp Sodium Salt
CAS No.	60777-99-3
Molecular Formula	C10H13N5O12P3S • xNa+
Molecular Weight	Contact for details
Synonyms	Adenosine 5'-(γ-thio)triphosphate sodium salt; ATPγS sodium salt; Adenosine 5'-(3-thiotriphosphate) sodium salt; γ-Thio-ATP sodium salt; ε-ATP Na salt; ATP-γ-S sodium salt; Adenosine-5'-triphosphorothioate sodium salt; Non-hydrolyzable ATP analog sodium salt
EINECS	Contact for details

Quality Control

Our ε-Atp Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and production use. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 85% (by UV)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.