Description

Cyclopropanecarbonyl Chloride, 2-Methyl- (6Ci, 9Ci) is a specialized organic acid chloride derivative of cyclopropane, serving as a critical building block in advanced synthetic chemistry. Its value lies in its highly reactive carbonyl chloride group, which enables efficient acylation and esterification reactions to construct complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the sterically constrained and bioactive cyclopropane moiety into target molecules. CAS number 60733-34-8.

Application

This versatile chemical intermediate is primarily employed in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) and drug candidates featuring the cyclopropane ring, known for its metabolic stability and conformational restriction.
• Agrochemical Synthesis: Production of herbicides, fungicides, and insecticides where the cyclopropane group can enhance biological activity and environmental persistence.
• Material Science Precursors: Building block for monomers and polymers with unique thermal and mechanical properties derived from the strained ring system.
• Chemical Research & Development: A key reagent in academic and industrial R&D for exploring new reaction pathways and creating novel chemical entities.
• Fine Chemical Manufacturing: Production of specialty chemicals, flavors, and fragrances requiring high-purity, custom-synthesized intermediates.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2-Methyl- (6Ci, 9Ci)
CAS No.	60733-34-8
Molecular Formula	C5H7ClO
Molecular Weight	118.56 g/mol
Synonyms	2-Methylcyclopropanecarbonyl chloride; (2-Methylcyclopropyl)carbonyl chloride; 2-Methylcyclopropanecarboxylic acid chloride; α-Methylcyclopropanecarbonyl chloride; Methylcyclopropanecarbonyl chloride; Cyclopropanecarboxylic acid, 2-methyl-, chloride; 60733-34-8 (CAS)
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.